photostability of drugs and drug formulations, Hanne Hjorth Tønnesen, 2nd, ingles

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Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource.

The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results.

Features

Assists non-experts in this field design a test protocol and interpret the results

Covers in vitro and in vivo aspects of interactions between drugs and light

Explores the kinetic and chemical aspects of drug photodecomposition

Discusses the problems frequently encountered in photochemical stability testing

Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs

Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint

Offers specific guidance in photostability testing and screening of drug photoreactivity

Stability of drugs and dosage forms, Sumic Yoshioka and Valentino J. Stella, ingles

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Drug products are complex mixtures of drugs and excipients and, as such, their chemical and physical stability kinetics are complex. This book discusses the stability of these dosage forms with preformulation studies through to the studies on the final products. The book is intended for graduate students, researchers and professionals in the field of Pharmaceutics and Pharmaceutical Chemistry.

Pharmaceutical preformulation and formulation, Mark Gibson, 2nd, ingles

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Written by a panel of experts, this book covers every stage of drug development, from candidate drug selection to commercial formulation. It provides practical reference and pragmatic guide on what studies need to be undertaken, for what reasons, and at what key stages of the drug development process. Going beyond coverage of preformulation, the book discusses biopharmaceuticals, drug delivery, formulation, and process development aspects of product development. The contributing authors share their experience and expertise in significant chapters divided into three useful sections: Aiding Candidate Drug Selection, Early Drug Development, and From Product Design to Commercial Dosage Form.